Research

JOURNAL PUBLICATIONS

A general health economics review of the hidden costs involved in discharging patients from hospital-based specialty clinics to community-based management

Non-Coeliac Gluten Enteropathy

Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case -control study

Accuracy of a no-biopsy approach for the diagnosis of coeliac disease across different adult cohorts

The correlation between vitamin D levels and demographics in patients with gastrointestinal disorders; a cross-sectional study

Consensus standards of healthcare for adults and children with inflammatory bowel disease in the UK

Predictors of anti-TNF Treatment failure in anti-TNF-naïve patients with active luminal Crohn’s disease: a prospective, multicentre, cohort study.

Developing a core outcome set for fistulising perianal Crohn’s disease

ROC-king onwards: intraepithelial lymphocyte counts, distribution & role in coeliac disease mucosal interpretation

Gluten-Free Diet Indications, Safety, Quality, Labels, and Challenges

Celiac disease: management of persistent symptoms in patients on a gluten-free diet.

Rebutting Oberhuber- Again; The Marsh III coeliac mucosal lesion does not need subdividing

Microscopic enteritis: Bucharest consensus.

How similar is biosimilar ? Crohn’s and Colitis UK, Clinical Communities, June 2015

Mucosal histopathology in celiac disease: a rebuttal of Oberhuber’s sub-division of
Marsh III. (Alternative text)

Early identification of patients with psychological distress: the role of inflammatory bowel disease nurses

Asacol + Assure. Working Better Together. Warner Chilcott Newsletter March 2014 Vol 2

Polymorphisms near TBX5 and GDF7 are associated with risk of Barrett’s oesophagus

Colonic diverticulosis: A review

Coeliac disease in the elderly: A review

Using bacterial biomarkers to identify early indicators of cystic fibrosis pulmonary exacerbation onset

Faecal calprotectin: a noninvasive diagnostic tool and marker of severity in pouchitis

Faecal M2-pyruvate kinase: a novel, noninvasive marker of ileal pouch inflammation

The medical management of patients with an ileal pouch anal anastomosis after restorative proctocolectomy.

Use of fecal lactoferrin to diagnose irritable pouch syndrome: A word of caution.

Malaria: The dilemmas of malarial diagnostics.

Hyperbaric oxygen as a treatment for malabsorption in a radiation damaged short bowel.

Risk of dysplasia and adenocarcinoma following restorative procto-colectomy for ulcerative colitis.

Presentation, diagnosis and management of inflammatory bowel disease in older people.

The pathogenesis of coeliac disease.

Bacterial community diversity in cultures derived from healthy and inflamed ileal pouches after restorative procto-colectomy. [Awaiting publication by IBD]

Osteoporosis in patients over 50 years of age following restorative proctocolectomy for ulcerative colitis: is DXA screening warranted?

The bacteriology of pouchitis: A molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing

Coeliac disease in the older patient: Are we ageist in our practice. [Accepted by Gastroenterology Today]

Prolonged toxic megacolon secondary to Salmonella. [Submitted]

11^th International Symposium on Coeliac Disease: A report. Gastroenterology Today 2006 P.5

Clinical toxicity of HMW glutenin subunits of wheat to patients with celiac disease. Proceedings of the 19^th Meeting of the Working Group on the prolamin analysis and toxicity, 2004; III Symposium: 147-9

Abstract / Poster Presentations

The incidence of Barretts oesophagus at a DGH endoscopy unit, and it’s associated conversion rate towards oesophageal cancer: A 10 year retrospective review (Abstract) + (UEGW Barretts Cancer Poster)

The use of PanEnteric Crohn’s Capsules to assess the treatment outcome of Vedolizumab in IBD patients: A 1 year proof of concept study. (Abstract) +(UEGW PECE & Vedo Poster)

The outcome of colonoscopic surveillance and surgery in a cohort of inflammatory bowel disease patients who developed colorectal cancer over a 12 year review period at a district general hospital. (Abstract) + (UEGW P0317 Outcome of IBD Surveillance Poster)

Prevalence of first time surgery amongst inflammatory bowel disease patients at a district general hospital: A 25 year retrospective review. (Abstract) + (UEGW P0512 Prevalence of first time surgery Poster)

Redo Surgery in IBD Patients: What is the Time Interval and Is This Affected by Specific Risk Factors?(Abstract) + (UEGW P0513 Redo Surgery in IBD Patients Poster)

Does the type of surgery or disease location predict the need for subsequent surgeries in IBD patients? (Abstract) + (UEGW P0514 Does the type of surgery predict Poster)

The changing trends seen with surgery in patients with inflammatory bowel disease over a 25 year review period.(Abstract) +(UEGW P0515 The changing trends seen with surgery Poster)

A 7 year retrospective review of iron deficiency anaemia in a catchment of 330,000 demonstrating the need for a dedicated anaemia service. (Abstract) + (Poster)

Global translation of coeliac disease histology and other gluten related microenteropathy. (Abstract) + (Poster)

Resource utilisation and cost associated with intravenous iron infusions inpatients with inflammatory bowel disease and iron deficiency anaemia or hypoferritaemia: real world evidence from the UK (Poster)

Clinical spectrum and treatment outcomes of eosinophilic oesophagitis in Durham and Tees Valley including initial results of orodispersible budesonide (Jorveza) (Poster)

Diagnosis of non-coeliac gluten sensitivity double blind placebo controlled gluten challenge versus open challenge approach (Poster)

Outcome of an Anaemia Service using the IBD-Registry

A 7 year Retrospective Analysis of the need for Repeated Course of Intra-venous Iron Therapy in IBD patients(Poster)

The cost burden of Coeliac Disease on a DGH Endoscopy Unit: A 12year retrospective review (Poster)

A 7 year Retrospective Analysis of the need for Repeated Course of Intra-venous Iron Therapy in Patients with Coeliac Disease (Poster)

Comparison between different types of self-management support in a group of IBD patients at the Luton & Dunstable University Hospital (Poster)

Slow transit constipation and Joint hypermobility syndrome: a case series in a district general hospital gastroenterology department

The Prevalence of Coeliac disease in our IBD Cohort (Poster)

Initial outcomes of an Anaemia Service Evaluation using the IBD Registry (Poster)

The incidence of Barrett’s Oesophagus at a DGH Endoscopy Unit, and its associated conversion rate towards Oesophageal Cancer: A 10y retrospective review (Poster)

The hospital admission burden of Coeliac disease: a 12 year retrospective analysis from a District General Hospital (Poster)

The outcome of lower gastrointestinal investigations in Coeliac disease: A 12 year retrospective review from a District General Hospital (DGH) perspective (Poster) 

The prevalence of Anaemia in Coeliac Disease, and the demand in this group for intravenous Iron Therapy (Poster)

The outpatient burden of coeliac disease on a district general hospital: An 11 year retrospective review (Poster)

Clinical outcomes of a personalised approach to the management of thiopurine drug therapy (Poster)

Is a false positive calprotectin as false as you think? (Poster)

The prevalence of anaemia in IBD, and demand for intra-venous iron infusion. (Poster)

Automated immunomodulator testing; Is it done by patients and are there useful lessons to be to learn when reviewing patient uptake of this service (Poster)

Interim data and experience in the IBD anaemia service evaluation project – a new role for the IBD Registry (Poster)

Monitoring unplanned care and surgical events for Crohn’s disease patients treated with biologics in England: Linkage of routine administrative data and UK IBD Registry (Poster)

Roc-King Onwards: IEL counts, distribution & roles in mucosal interpretation (Poster)

The financial burden of narcotic bowel syndrome: A local experience  – (Poster NBS Finances)

Narcotic bowel syndrome: A local experience of hidden burden – (Poster NBS Burden)

Stopping biological therapy in patients with inflammatory bowel disease: A 5 year review of a single centre’s experience – (Poster Stopping Biologicals)

The clinical outcomes of a personalised approach to the management of patients taking thiopurine medication, using metabolite assessments – (Poster TGN Clinical Outcomes)

Local experience of using tacrolimus as rescue therapy in resistant IBD – (Poster )

The outcomes and benefits of moving stable inflammatory bowel disease patients from a paper based self management system to a Supported, Self Help And Management Programme (IBD-SSHAMP) with specialist overview. – (Poster IBD-SSHAMP 2015)

The cost savings seen after introducing a thiopurine metabolite service into a district general hospital – (Poster TGN Financial Outcomes)

Is a false positive faecal calprotectin as false as you think?  – (Poster SBCE +FC)

Coeliac – Supported, Self Help And Management Programme (C-SSHAMP) UK’s first remote web-based management system for stable coeliac patients – (Poster C-SSHAMP)

Anti TNF withdrawal in IBD: Relapse and recapture rates and predictive factors from 160 patients in a pan-UK study

Using the National IBD Registry to prove the worth of the specialist nurse Nurses presentations: Nurses poster presentations (2014)

The use of faecal calprotectin in IBD and reducing unnecessary colonoscopy Poster presentations: Clinical: Diagnosis & outcome (2014)

A 10 year review of the death rate and cause of death of IBD patients Poster presentations: Epidemiology (2014) – (Poster P645. 10 year review of IBD death rate and cause)

Is there an association between inflammatory bowel disease and Parkinson’s disease? Poster presentations: Epidemiology (2014) – (Poster P611. Association between IBD + PD ?)

Inflammatory bowel disease: A 10 year review of the cost and demand of this condition, on a district general endoscopy unit. GUT 2013. 62; Suppl 1: A274 (PTH-156)

The effect of ethnicity on the prevalence of IBD with the Luton and Dunstable catchment region, in UK. GUT 2013. 62; Suppl 1:  A169-A170 (PWE-097)

The outpatient burden of inflammatory bowel disease : A 10 year review. GUT 2013. 62; Suppl 1:  A272 (PTH-154)

The Hospital admission burden of inflammatory bowel disease: A 10 year review from a DGH. GUT 2013. 62; Suppl 1:  A274 (PTH-155) 

Do we need to screen our IBD patients for depression: The prevalence and severity of depressionin IBD patients. GUT 2013. 62; Suppl 1: A244 (PTH-080)

IBD-SSHAMP (Supported, Self Help And Management Programme); UK’s 1st internet based remote management system for stable IBD patients. GUT 2013. 62; Suppl 1:  A34-35 (OCO-080) Winner – Best Oral Presentation in Health Informatics

Acceptance and adjustment in a district general cohort of IBD patients: Findings and Implications. GUT 2013. 62; Suppl 1:  A175-A176 (PWE-110)

Is there an association between Parkinson’s disease and IBD? GUT 2013. 62; Suppl 1:  A169 (PWE-096)

A 10 year review of death rate and cause of death within a DGH cohort of IBD patients. GUT 2013. 62; Suppl 1: A169 (PWE-095)

Assessment and implications of Health-Related QOL in a DGH cohort of IBD patients. GUT 2013. 62; Suppl 1: A176 (PWE-111)

The use of faecal calprotectin in routine clinical practice can help avoid dilemma and significantly reduce unnecessary colonoscopy. GUT 2013. 62; Suppl 1: A275 (PTH-157) Winner of a Poster of Distinction

Unearthing the true prevalence of anxiety within IBD patients: Is it time we considered routinely screening for anxiety. GUT 2013. 62; Suppl 1: A244 (PTH-081)

Outcome assessment of the first 2 years of a new oesophageal high resolution unit within a DGH. GUT 2013. 62; Suppl 1: A281 (PTH-172)

The outcome of pouch surgery in older patients. GUT 2008; 57 (Suppl I, Vol 57): A135

The role of macrophages and lymphocytes in acute pouchitis. GUT 2008; 57 (Suppl I, Vol 57): A119

Clinical experience with VSL#3 in patients with chronic pouchitis. GUT 2008; 57 (Suppl I, Vol 57): A136

Osteoporosis in patients over 50 following restorative procto-colectomy for ulcerative colitis; Is DEXA screening warranted. GUT 2008; 57 (Suppl I, Vol 57): A89

Evidence for a bacterial dysbiosis in pouchitis after restorative procto-colectomy using 16srRNA sequencing: Preliminary report of an ongoing study. GUT 2008; 57 (Suppl I, Vol 57): A123

Training in small bowel capsule enteroscopy and assessment of competency. BRIGHTON Regional BSG 2007

Investigation and Management of patients referred with non-responsive coeliac disease: Results of 110 cases. GUT 2007; 56 (Suppl II): A57

Immunofluorescence Studies: Does IL15 play a role in the pathogenesis of pouchitis. GUT 2006; 55 (Suppl II, Vol 38): A104

The characterisation of bacterial community diversity in cultures derived from healthy and inflamed ileal pouches after restorative procto-colectomy, using 16S ribosomal DNA terminal restriction fragment length polymorphism (T-RFLP) profiling. GUT 2006; 55 (Suppl II, Vol 38): A104

Faecal calprotectin and M2-PK as a diagnostic tools for pouchitis. ACB FOCUS 2006 BIRMINGHAM Biochemistry Conference: W18

Faecal M2-pyruvate kinase; a novel, non-invasive marker of ileal pouch information. Gastroenterology P.217756

High yield of colonoscopy in investigating celiac patients with     diarrhoea. GUT. 2005; 55(Suppl II): 378

A comparative study of the presentation and investigation of coeliac disease in both elderly and young patients. GUT 2005; 54 (Suppl VII): A134

Nutritional deficiencies in ileal pouch patients. GUT 2005; 54 (Suppl VII): A235

Does pouchitis occur in familial adenomatous patients? GUT 2005; 54 (Suppl VII): A237

A survey of microscopic colitis management in the south-east        Thames region. ECCP/EACP Second Joint Meeting Abstarct Book; P071

High prevalence of abnormal duodenal histology in asymptomatic coeliac patients. GUT 2005; 54(Suppl II): 401

Audit of treatment pathway and quality of life for community patients with PEGs. GUT 2004; 53(Suppl III): 292

Non-responsive coeliac disease – experience of a teriary referral centre. GUT 2004; 53(Suppl III): 021

Screening of relatives of patients with coeliac disease. GUT 2004; 53(Suppl III): 273

Microscopic colitis association and treatment outcomes in the short and long-term: A retrospective study.  Brighton 2001. Regional BSG poster presentation

The clinical features of patients with varicose veins referred to the vascular unit. Vascular Conference Corfu 1996

Do Patients with varicose veins have an increased incidence of restless leg syndrome, nocturnal cramps and peripheral neuropathy. Vascular Conference Corfu 1996

Oral Presentations

British Socoety of Gastroenterology – 2007  Glasgow, UK

The characterisation of bacterial community diversity in cultures derived from healthy and inflamed ileal pouches after restorative procto-colectomy, using 16S ribosomal DNA terminal restriction fragment length polymorphism (T-RFLP) profiling.  GUT 2007; 56 (Suppl II): A5

European Council of Coloproctology + European association of Coloproctology – Bologna, Italy 2005

Does pouchitis occur in familial adenomatous patients? Second Joint Meeting Abstract Book; P071

Awarded one of the “Best Five Abstracts Presentation”

The 11th International Symposium of Coeliac Disease – Belfast 2004

A comparative study of the presentation and investigation of coeliac disease in both the elderly and young.

REGIONAL BSG 2005 – Brighton

Medical considerations to the management of ileal pouch patients

St. MARK’S STOMA NURSE SPECIALIST DAY – 2005

Management of Pouchitis and Cuffitis

THE NATIONAL POUCH PATIENTS SUPPORT DAY – 2004

St. Mark’s Hospital, “Red Lion” Pouch Patients Support Group

Pouchitis and Probiotics